Key words: supercritical fluid extraction, supercritical fluid chromatography, Ammi Majus, bergapten, xanthotoxin, isopimpinellin
A method of supercritical fluid extraction of furocoumarin components from the seeds of apiaceous plant Ammi Majus is developed. Linear furocoumarins from Ammi Majus: bergapten, xanthotoxin and isopimpinellin — are used as photosensitizers in PUVA-therapy — photochemotherapy of various skin deseases. A method for chromatographic detection and separation of these furocoumarins using supercritical fluid chromatography is established.
doi:10.1134/S1990793109080065