O.V. Filonova, A.V. Lekar, S.N. Borisenko, E.V. Vetrova, E.V. Maksimenko, N.I. Borisenko, V.I. Minkin
Hydrolysis of Aralosides from Aralia Manchurian in Subcritical Water to Oleanolic Acid and its Derivatives
A method to obtain oleanolic acid (OA) and its derivatives by hydrolysis of aralia
manchurian in subcritical water is developed. It is carried out on an example of
pharmaceutical preparation «Saparal» at 120—240 °C in static regime. A maximal yield
of OA is obtained at 210 °C.
Key words: subcritical water, aralosides, aralia manchurian, saponins, saparal, oleanolic acid, HPLC-MS
Full text (PDF)