Сверхкритические флюиды. Теория и практика
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2015, N2, pp. 31-39

O.V. Filonova, A.V. Lekar, S.N. Borisenko, E.V. Vetrova, E.V. Maksimenko, N.I. Borisenko, V.I. Minkin

Hydrolysis of Aralosides from Aralia Manchurian in Subcritical Water to Oleanolic Acid and its Derivatives

A method to obtain oleanolic acid (OA) and its derivatives by hydrolysis of aralia manchurian in subcritical water is developed. It is carried out on an example of pharmaceutical preparation «Saparal» at 120—240 °C in static regime. A maximal yield of OA is obtained at 210 °C.

Key words: subcritical water, aralosides, aralia manchurian, saponins, saparal, oleanolic acid, HPLC-MS

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