Сверхкритические флюиды. Теория и практика
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2015, N4, pp. 36-41

E.N. Antonov, A.G. Dunaev, V.K. Popov

Study of Acetylsalicylic Acid Solubility in Supercritical Carbon Dioxide

Solubility of acetylsalicylic acid (ASA) in supercritical carbon dioxide (SC-CO2) is studied using FTIR spectroscopy by measuring the integral intensities of the ASA absorption band in the region of 1199 cm-1 as the function of time during the dissolution of varied amounts of ASA placed into the cell. The mole fractions of ASA in its saturated solutions in SC-CO2 at 40 °C are (2.1 ± 0.25) ⋅10-4 and (11.0 ± 1.5) ⋅10-4 at 10.0 and 15.0 MPa, respectively.

Key words: acetylsalicylic acid, supercritical carbon dioxide, FTIR spectroscopy, solubility

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