Key words: subcritical water, aporphine alkaloids, glaucine, phenanthrene alkaloids, seco-glaucine, HPLC
The synthesis of phenanthrene alkaloid seco-glaucine from herbal aporphine alkaloid
glaucine in subcritical water is studied at 100—250 °C with no catalytic additived. The
maximum product yield (∼ 80 %) that is reached at 250 °C is virtually independent on
the amount of the initial compound. The product can be directly preci pitated from the
reaction mixture if its concentration is sufficiently high. No use of constly and toxic
organic solvents is required.
doi:10.1134/S1990793117080140