«One-Pot» Technique for Production of Glycyrrhetinic Acid from the Roots of Licorice (Glycyrrhiza glabra L.) by Subcritical Water

2018, №4

сс. 19-27

A.V. Lekar, E.V. Maksimenko, S.N. Borisenko, S.S. Khizrieva, E.V. Vetrova, N.I. Borisenko, V.I. Minkin

Key words: «one-pot», subcritical water, glycyrrhetinic acid, roots of licorice Glycyrrhiza glabra L.

For the first time starting from the roots of licorice Glycyrrhiza glabra L. the
glycyrrhetinic acid (GLA) was obtained in a good yield using an «one-pot» method in
medium of subcritical water (SBW) that serves as a reactant and a solvent. This method
of preparation of GLA allows one to avoid the use of toxic organic solvents and does
not require the separate stages of extraction and hydrolysis. The good yields of the
targeted GLA can be obtained for the period, which is ten times shorter than needed
by the traditional procedures. The proposed method is promising for the future
development of low-cost and environment friendly technologies for GLA producing
in pharmaceutical, food and cosmetic industries.

Translated article

doi:10.1134/S1990793119070170

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ГОСТ
7.0.100-2018

Лекарь, А.В. «One-Pot» Technique for Production of Glycyrrhetinic Acid from the Roots of Licorice (Glycyrrhiza glabra L.) by Subcritical Water / А.В. Лекарь, Е.В. Максименко, С.Н. Борисенко [и др.]. – Текст : непосредственный // Сверхкритические Флюиды: Теория и Практика.. – 2018. – Т. 13. – № 4. – С. 19-27. - DOI: 10.34984/SCFTP.2018.13.4.003

TRANSLIT

Lekar', A.V. Ispol'zovanie «One-Pot» metoda dlya polucheniya glicirretinovoj kisloty iz kornej solodki (Glycyrrhiza glabra L.) v srede subkriticheskoj vody / A.V. Lekar', E.V. Maksimenko , S.N. Borisenko [i dr.]. – Sverhkriticheskie Flyuidy: Teoriya i Praktika.. – 2018. – Т. 13. – № 4. – S. 19-27. - DOI: 10.34984/SCFTP.2018.13.4.003

A.V. Lekar, E.V. Maksimenko, S.N. Borisenko, S.S. Khizrieva, E.V. Vetrova, N.I. Borisenko, V.I. Minkin «One-Pot» Technique for Production of Glycyrrhetinic Acid from the Roots of Licorice (Glycyrrhiza glabra L.) by Subcritical Water. Sverhkriticheskie Flyuidy: Teoriya i Praktika, 4, 19-27 (2018). https://doi.org/10.34984/SCFTP.2018.13.4.003

«One-Pot» Technique for Production of Glycyrrhetinic Acid from the Roots of Licorice (Glycyrrhiza glabra L.) by Subcritical Water

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