2008, №1

сс. 5-23

The Use of Supercritical Fluids for The Production of Nano- and Microforms of Pharmaceutical Substances

2008, №1

сс. 5-23

Цитировать

D.Yu. Zalepugin, N.A. Tilkunova, I.V. Chernyshova

Key words: supercritical fluids, nanoparticles, microparticles, pharmaceutical substances, liposomes

The preferences of drugs on the base of nano- and microparticles are reviewed in
        comparison with traditional drug forms. The application of supercritical fluids for the
        production of nano- and microforms of pharmaceutical substances including drug
        delivery systems on the base of polymers and liposomes is discussed. The methods
        based upon the use of supercritical fluids, such as RESS, GAS, ASES, SAS, SEDS were
        shown to be of the most value for the production of nano- and microforms of drugs.