Key words: supercritical fluids, nanoparticles, microparticles, pharmaceutical substances, liposomes
The preferences of drugs on the base of nano- and microparticles are reviewed in
comparison with traditional drug forms. The application of supercritical fluids for the
production of nano- and microforms of pharmaceutical substances including drug
delivery systems on the base of polymers and liposomes is discussed. The methods
based upon the use of supercritical fluids, such as RESS, GAS, ASES, SAS, SEDS were
shown to be of the most value for the production of nano- and microforms of drugs.