2018, №3

сс. 45-55

Chiral Supercritical Fluid Chromatography of 1,2-Aminoalcohols

2018, №3

сс. 45-55

Цитировать

K.V. Gensh, T.S. Gensh, N.G. Bazarnova

Key words: supercritical fluid chromatography, preparative SFC, 1,2-aminoalcohols, pharmaceutical substances

Preparative separation of enantiomers is one of the most common applications of
supercritical fluid technologies in modern production practice. In this review, methods
for the preparative separation of enantiomers of pharmaceutical substances in which
a 1,2-amino alcohol moiety is present are provided, using supercritical fluid
chromatography. The types of chiral phases used in supercritical fluid chromatography
are also briefly considered.

doi:10.1134/S1990793119070066