2015, №1

pp. 3-8

Synthesis of Glycyrrhetinic Acid Monoglycoside by Hydrolysis of Glycyrrhizic Acid in Subcritical Water

2015, №1

сс. 3-8

Quote

O.V. Filonova, A.V. Lekar, S.N. Borisenko, E.V. Maksimenko, E.V. Vetrova, N.I. Borisenko, V.I. Minkin.

Key words: ammonium glycyrrhizinate, glycyram, glycyrrhizic acid, glycyrrhetinic acid, monoglycoside of glycyrrhetinic acid, electrospray ionization mass spectrometry, HPLC-MS, subcritical water

A method for synthesis of glycyrrhetinic acid monoglycoside by hydrolysis of glycyrrhizic acid in subcritical water at temperatures between 100 and 300 °C is developed. The maximum yield of the target product is obtained at 160 °C.