Key words: paracetamol, supercritical CO2, phase equilibrium, solubility, heat capacity, dispersing using SEDS method
Solubility of paracetamol in supercritical carbon dioxide and its mixtures with acetone is experimentally studied. Isobaric heat capacities of paracetamol and «paracetamol — SC—CO2», «paracetamol — acetone — SC—CO2» systems at 303—523 K and 7—29 MPa are measured. The results of paracetamol dispersing using the SEDS (Solution Enhanced Dispersion by Supercritical Fluids) method are presented.