«One-Pot» Technique for Production of Glycyrrhetinic Acid from the Roots of Licorice (Glycyrrhiza glabra L.) by Subcritical Water

2018, №4

сс. 19-27

A.V. Lekar, E.V. Maksimenko, S.N. Borisenko, S.S. Khizrieva, E.V. Vetrova, N.I. Borisenko, V.I. Minkin.

Key words: «one-pot», subcritical water, glycyrrhetinic acid, roots of licorice Glycyrrhiza glabra L.

For the first time starting from the roots of licorice Glycyrrhiza glabra L. the glycyrrhetinic acid (GLA) was obtained in a good yield using an «one-pot» method in medium of subcritical water (SBW) that serves as a reactant and a solvent. This method of preparation of GLA allows one to avoid the use of toxic organic solvents and does not require the separate stages of extraction and hydrolysis. The good yields of the targeted GLA can be obtained for the period, which is ten times shorter than needed by the traditional procedures. The proposed method is promising for the future development of low-cost and environment friendly technologies for GLA producing in pharmaceutical, food and cosmetic industries.

doi:10.34984/SCFTP.2018.13.4.003

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ГОСТ
7.0.100-2018

Лекарь, А.В. «One-Pot» Technique for Production of Glycyrrhetinic Acid from the Roots of Licorice (<i>Glycyrrhiza glabra</i> L.) by Subcritical Water / А.В. Лекарь, Е.В. Максименко, С.Н. Борисенко [и др.]. – Текст : непосредственный // Сверхкритические Флюиды: Теория и Практика.. – 2018. – Т. 13. – № 4. – С. 19-27. - DOI: 10.34984/SCFTP.2018.13.4.003

TRANSLIT

Lekar', A.V. Ispol'zovanie «One-Pot» metoda dlya polucheniya glicirretinovoj kisloty iz kornej solodki (Glycyrrhiza glabra L.) v srede subkriticheskoj vody / A.V. Lekar', E.V. Maksimenko , S.N. Borisenko [i dr.]. – Tekst : neposredstvennyj // Sverhkriticheskie Flyuidy: Teoriya i Praktika.. – 2018. – Т. 13. – № 4. – S. 19-27. - DOI: 10.34984/SCFTP.2018.13.4.003

A.V. Lekar, E.V. Maksimenko, S.N. Borisenko, S.S. Khizrieva, E.V. Vetrova, N.I. Borisenko, V.I. Minkin «One-Pot» Technique for Production of Glycyrrhetinic Acid from the Roots of Licorice (<i>Glycyrrhiza glabra</i> L.) by Subcritical Water. Sverhkriticheskie Flyuidy: Teoriya i Praktika, 4, 19-27 (2018). https://doi.org/10.34984/SCFTP.2018.13.4.003

«One-Pot» Technique for Production of Glycyrrhetinic Acid from the Roots of Licorice (Glycyrrhiza glabra L.) by Subcritical Water

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