Key words: sodium alginate, chitosan, supercritical drying, aerogel, interpolymer complex, furacilin
Composite aerogel materials based on the alginate-chitosan interpolyelectrolyte complex with calcium carbonate using supercritical fluids were obtained. Aerogels have developed mesoporous structure. The specific surface area of the samples is 400 m2g-1, the average pore size is 19.3 nm, and the total pore volume is 1.93 cm3g-1. New materials are superadsorbents. 1 g of aerogel retains 60 g of liquid while maintaining its shape. The possibility of using the obtained composite aerogels to create wound coatings with the inclusion of an antiseptic medicinal substance (furacilin) was shown. It was found that for all samples of aerogels, the furacilin release profile from the aerogel matrix corresponds to the dynamics of controlled release. It was shown that within 5 hours there is almost complete release of furacilin (88—95 %) from the aerogel matrix, which is due to the developed surface of the material.
doi:10.34984/SCFTP.2020.15.3.002