Сверхкритические флюиды. Теория и практика
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2018, N3, pp. 45-55

K.V. Gensh, T.S. Gensh, N.G. Bazarnova

Chiral Supercritical Fluid Chromatography of 1,2-Aminoalcohols

Preparative separation of enantiomers is one of the most common applications of supercritical fluid technologies in modern production practice. In this review, methods for the preparative separation of enantiomers of pharmaceutical substances in which a 1,2-amino alcohol moiety is present are provided, using supercritical fluid chromatography. The types of chiral phases used in supercritical fluid chromatography are also briefly considered.

Key words: supercritical fluid chromatography, preparative SFC, 1,2-aminoalcohols, pharmaceutical substances


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