Key words: chitosan, alginate, magnetite, aerogel, supercritical fluid technologies.
Composite aerogels were obtained based on two-component sodium alginate—chitosan hydrogels with the inclusion of magnetite and subsequent drying in supercritical carbon dioxide. The optimal concentration of magnetite introduced into the sodium alginate— chitosan system and the mode of supercritical drying of composite hydrogels in the carbon dioxide were experimentally established, making it possible to obtain the aerogel with a maximally developed porous structure. Using the method of low-temperature nitrogen adsorption, it was shown that the resulting aerogels are characterized by a developed mesoporous structure with open cylindrical pores, the maximum specific surface is 300 m2/g. Experimental studies have shown that the developed composite magnetite-containing aerogels have high bactericidal activity against S. aureus, E. coli and B. subtilis, due to which they have great potential for creating various medical products based on them, including wound dressings, carriers active medicinal substances, hemostatic or sorption materials.
doi:10.1134/S1990793124701707