Key words: supercritical carbon dioxide, biological matrix, xenogenic bone tissue, resorbability, polylactide
A method for producing new generation of xenogenic biomatrixes, which are
characterized by their special purity and suitable for implantation in a living organism,
is proposed by additional treatment with supercritical carbon dioxide. The obtained
highly pure biomatrixes were modified by introducing dosed amounts of polylactides
with a molecular weight of 20 and 40 KDa into their pore space. In vivo testing of the
obtained materials showed their high biocompatibility with varying degrees of
integration with surrounding tissues.
doi:10.1134/S1990793120070064